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The science and vision behind IQOS

IQOS is the combination between science, technology and vision.

Science

We believe in science. We believe it can change the lives of millions of smokers, who would otherwise continue to smoke. To this effect, we recruited scientists to work on an important idea: developing less harmful products that cigarette smokers can switch to if they don’t quit. Hundreds of scientists and engineers at PMI’s global Research and Development centers in Switzerland and Singapore have developed and evaluated IQOS, an innovative electronic device that heats and not burns tobacco. It produces a tobacco vapor that delivers tobacco taste and nicotine.

Tested to the highest standards

IQOS has gone through robust scientific assessments, including, to date, 18 non-clinical and 10 clinical studies involving thousands of participants. The totality of evidence available shows that, while IQOS use is not risk-free, switching completely to IQOS presents less risk to your health than continuing to smoke cigare

Do you want to find out why we can conclude this? Learn more about some of the key pieces of scientific evidence on IQOS.

Why is heating better

Technology – the world revolves around it. Over the years, it has radically changed our lives for the better. The way we work, the way we communicate, the way we travel. By combining science and technology is how we developed a better alternative to continued smoking.

IQOS is changing for the better the way adult smokers, who would otherwise continue to smoke, can enjoy tobacco.

IQOS heats tobacco instead of burning it for a simple reason: the burning of tobacco emits high amounts of harmful chemicals. IQOS HeatControl™ Technology prevents tobacco from burning, which means it significantly reduces the number and level of harmful chemicals emitted compared to cigarette smoke.

Heating technology

When a cigarette is lit, the tobacco burns at temperatures of around 600°C. This burning process generates smoke and ash; when a smoker takes a puff, the temperature rises above 800°C at the burning tip. Cigarette smoke is a complex mixture of over 6000 chemical substances, around 100 of which have been to linked smoking-related diseases by public health authorities.

IQOS HeatControl™ Technology heats tobacco to a lower temperature (less than 350°C), ensuring that combustion does not occur. Because there is no combustion, IQOS does not produce smoke. It generates a tobacco vapor that brings you a high-quality tobacco taste experience with 95% less harmful chemicals compared to cigarettes.

Important information: It does not necessarily equal a 95% reduction in risk. IQOS is not risk-free.

* ”95% less” represents the average reductions in levels of a range of harmful chemicals (excluding nicotine) compared to the smoke of a reference cigarette (3R4F). See Important Information..

Tobacco vapor vs Smoke

IQOS tobacco vapor is less harmful than cigarette smoke. To demonstrate this, we conducted a comprehensive assessment program that included 10 clinical studies on aerosol chemistry (as well as data from 18 non-clinical studies), and involved thousands of participants in the US, Japan, UK and Poland. Evidence demonstrates that switching completely to IQOS, while not risk-free, presents less risk of harm compared with continuing to smoke cigarettes.

Is IQOS less toxic?

In laboratory settings, we found that IQOS’ tobacco vapor is less toxic than cigarette smoke. Our scientists test our products thoroughly before they go into adult smokers’ hands. Using in vitro assays in our labs, we assessed the cytotoxicity and genotoxicity of IQOS tobacco vapor in comparison with the smoke of a reference cigarette designed for research purposes. Taken together, the results of these assays show that IQOS tobacco vapor is significantly less toxic than the smoke from reference cigarette. This is just a glimpse of our work. These tests were crucial before we moved on to test IQOS with thousands of adult smokers who voluntarily participated in our clinical study program and ultimately allowed us to commercialize our products.

Authorized in the US as a Modified Risk Tobacco Product

The FDA or Food & Drug Administration is a federal agency within the United States Department of Health and Human Services. It is responsible for regulating the manufacturing, marketing, and distribution of tobacco products in the US.

IQOS is the first and only tobacco heating system authorized in the US as a Modified Risk Tobacco Product with reduced exposure information.

Important information: IQOS is not risk-free. It delivers nicotine, which is addictive.

Source: FDA’s marketing order for the IQOS system dated July 7, 2020.

Indoor Air Quality

Indoor Air Quality (“IAQ”) refers to the air quality inside buildings, generally based on the principle of ensuring the health and comfort of the occupants. Temperature, humidity and contaminants are some of the factors that can affect the indoor air quality. But, human presence and activities such as cooking, cleaning or smoking have been proven to have considerable impact.

To enhance our knowledge and understanding the impact of IQOS on indoor air quality we conducted studies simulating “real-world” conditions in an environmentally controlled room. Our testing methods are validated, and ISO accredited.

Our study shows that, because IQOS does not burn tobacco and it does not generate smoke. it does not negatively impact indoor air quality. This means that the few compounds we nevertheless detected were found at very low concentrations and far below the maximum exposure levels defined in existing air quality guidelines.

Science machine

Did you know we’ve created a machine to show the significant differences between smoke produced by burning tobacco in a cigarette compared to the tobacco vapor generated when tobacco is heated in IQOS? Watch the science machine video to see more.

The result

IQOS is a better choice than continued smoking.
The totality of scientific evidence available to-date clearly demonstrates that switching completely to IQOS presents less risk to your health than continuing to smoke cigarettes.*

Important information: IQOS is not risk free. It delivers nicotine, which is addictive. IQOS is not risk free and delivers nicotine, which is addictive. The best decision any smoker can make is to quit tobacco and nicotine use altogether.

* Source: Based on the totality of evidence available for IQOS in comparison with continuing to smoke, which includes data on aerosol chemistry from 10 clinical studies conducted with thousands of participants in the US, Japan and Poland, and data from 18 non-clinical studies.

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We care. This website has information about smoke-free products, which are for adults who would otherwise continue to smoke or use other nicotine products in Ukraine. PMI’s smoke-free products are not an alternative to quitting and are not designed as cessation aids.
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